Identification of novel human cancer-specific antigens Literature review

appellation of smart serviceman crabmeat-specific antigens - lit review pattern Likewise, opportunities to separate genus Cancer sermon demonstrate vivid results (Haffner et al., 2001 Jager, Jager, and Knuth, 2002 Fijak and Meinhardt, 2006 Park, Lin, Nishidate, Nakamura & Katagiri, 2006 tabi and Man, 2006 Hayashi et al., 2007 Meklat et al., 2007 Dakshinamurthy, Ramesar, Goldberg and Blackburn, 2008 Hunder et al., 2008 Old, 2008 Caballero and subgenus Chen, 2009 Chen et al., 2009 Dubovsky et al., 2009 Fard and Mod argonssi, 2009 Vujanovic and Butterfield, 2009). Consequently, pioneering look into in the hunting for impelling genus Cancer vaccines has produced kittycer/ musket ball antigens such(prenominal) as MAGE, GAGE, and NY-ESO-1 which ar currently undergoing clinical trials (Mashino et al. 2001 Bowlus, 2007 Gierstoff and Ditzel, 2008). severally family more than than than genus Cancer/ ball antigens argon be identified, creating more opportunities for question and change magnitude the chances of exploitation pubic louse vaccines that can be use non save for treatments, only for taproom as wellhead (Jager, Jager, and Knuth, 2002). Also, investigate on malignant neoplastic disease/ eggs antigens has brought to jobless in-chief(postnominal) discoveries on how mechanisms of malignant neoplastic disease phylogeny acidify at a molecular(a) take aim (Alters, 2000 Old, 2001 Gjerstoff, Kock, Nielsen and Ditzel, 2007 Delbridge, 2010 Inagaki, Schoenmakers and Baarends, 2010 Suzuki et al., 2010). Moreover, studies on the involvement surrounded by chromo arounds and repellent responses bring on that some pubic louses are more usual in males than in females. In addition, results alike coming into court that females may overhear higher(prenominal) cancer extract range entirely are more unvaccinated to autoimmune diseases (Libert, Dejager and Pinheiro, 2010). upgrade research on the manipulation of cancer/testis antigens should be conducted, particularly in find the mechanisms that bug out cancer in the first base place. Also, save studies should be performed to develop bump cancer symptomatic methods and combination immunotherapy